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Cell fixation improves performance of in situ crosslinking mass spectrometry while preserving cellular ultrastructure

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Abstract Crosslinking mass spectrometry (XL-MS) has the potential to map the interactome of the cell with high resolution and depth of coverage. However. current in vivo XL-MS methods are hampered by crosslinkers that demonstrate low cell permeability and require long reaction times. Consequently. https://parisnaturalfoodes.shop/product-category/saw-palmetto-plus-for-women/
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