Advances in the field chronobiology have potential implications for physical as well as mental health and human behavior. Several paradigm-shifting discoveries established key mechanistic principles for the biological clock. We trace the origins and key discoveries that helped to advance the field of chronobiology and a ground-breaking work recently recognized by Nobel prize. https://www.bekindtopets.com/mega-sale-Israel-Flag-Distressed-iPhone-14-Pro-Max-Folio-Case-p26681-top-mega/