Abnormal processing of TAR DNA binding protein 43 (TDP-43) has been identified as a major factor in neuronal degeneration during amyotrophic lateral sclerosis (ALS) or frontotemporal lobar degeneration (FTLD). It is unclear how changes to TDP-43. including nuclear to cytosolic translocation and subsequent accumulation. are controlled in these diseases. https://safeersappliancers.shop/product-category/aeg-kme761000b-built-in-combination-microwave-oven-and-grill-in-black/